Package of medications for treating bacterial vaginosis (BV) against a red background

How to Treat Bacterial Vaginosis (BV): Medications and Home Remedies

Medically reviewed on June 27, 2023 by Morgan Spicer, Medical Communications Manager. To give you technically accurate, evidence-based information, content published on the Everlywell blog is reviewed by credentialed professionals with expertise in medical and bioscience fields.


Table of contents


Bacterial vaginosis (BV) is the most common vaginal problem experienced by people assigned female at birth (AFAB) of reproductive age. [1] BV isn’t considered a sexually transmitted infection; however, it is still closely related to sexual and reproductive health. Let’s take a closer look at the causes and treatment options for BV.

Causes of Bacterial Vaginosis

Bacterial vaginosis is caused by an imbalance of certain kinds of bacteria within the vaginal microflora. [1] Similar to the gut, the vagina hosts useful bacteria that are responsible for maintaining a healthy vaginal pH and limiting the overgrowth of unwanted microorganisms or yeast. [2] When the balance of this bacteria is disrupted, bacterial vaginosis can occur. Some common causes of BV include sexual activity, douching, and the use of antibiotics. [1] Learn: How to Prevent BV

Additionally, there are some factors that may increase the risk of getting BV. These include [1,3,4]:

  • Frequent douching
  • Use of an intrauterine device (IUD)
  • Having a partner who is AFAB
  • Pregnancy
  • New or multiple sex partners
  • Unprotected sex
  • Cigarette smoking
  • Being HIV positive

How to Treat BV

Fortunately, BV is a curable condition that can be treated with antibiotics and other medications. Nearly 30% of BV cases will resolve without treatment; however, a majority of people affected by BV can benefit from medical intervention. [1]

Antibiotics and Antimicrobials

The first-line treatment for most people with bacterial vaginosis is a course of antibiotics. Antibiotics are medicines that kill bacteria and/or prevent bacteria from growing. [5] Antibiotics come in a few different forms, including [5]:

  • Oral pills, tablets, or liquids
  • Topical creams, gels, sprays, ointments, or drops
  • Injections or intravenously (IV)

Antimicrobials are agents that work to reduce the possibility of infection and sepsis. [6] While all antibiotics are a type of antimicrobial, not all antimicrobials are antibiotics. A simple way to explain the difference is that antibiotics target and kill bacteria, while antimicrobials target and kill bacteria, fungi, viruses, and other organisms. [6]

Metronidazole

Metronidazole is a commonly prescribed antibiotic for various bacterial infections, including respiratory tract infections, some sexually transmitted infections, meningitis, and others. [7] When prescribed for BV, metronidazole often comes in the form of a vaginal suppository, meaning it is inserted inside the vagina. [4] Metronidazole can also be prescribed as an oral tablet [4] Metronidazole is FDA-approved for many different bacterial infections and is generally considered safe; however, there are some potential side effects. [7] Some adverse effects of metronidazole can include [7]:

  • Headache
  • Vaginitis (vaginal inflammation)
  • Nausea
  • Metallic taste
  • Diarrhea
  • Dizziness
  • Abdominal pain

Clindamycin

Clindamycin is another common antibiotic. It is often used to treat infections such as strep throat, lower respiratory infections, pelvic inflammatory disease, and others. [8] Clindamycin is also available in various forms, including a gel, foam, lotion, solution, and oral capsule. For the treatment of bacterial vaginosis, clindamycin is often prescribed as a vaginal suppository, but may also be prescribed orally. [4] The side effects can vary depending on the mode of administration, but some potential effects include [8]:

  • Burning sensation
  • Itching
  • Inflammation
  • Yeast infection
  • Nausea and vomiting
  • Diarrhea

Tinidazole

While clindamycin and metronidazole are the two most frequently prescribed antibiotics for BV, alternative regimes are available. [4] If first-line treatments are not effective or there are allergy risks, other antimicrobial agents such as tinidazole can be used. Tinidazole is often used to treat infections caused by parasites, bacteria, and other microorganisms. [9] Tinidazole is often prescribed as an oral tablet, and may potentially cause side effects such as [9]:

  • Metallic or bitter taste
  • Fatigue
  • Dizziness
  • Headache
  • Heartburn
  • Nausea

Secnidazole

Secnidazole is another alternative regime used to treat bacterial vaginosis as well as some sexually transmitted infections. [4, 10] Secnidazole is an antimicrobial agent often prescribed as an oral tablet. This medication is usually well tolerated, but some side effects may occur, such as [10]:

  • Metallic or bitter taste
  • Headache
  • Nausea
  • Diarrhea
  • Abdominal pain

How to Treat BV at Home

Some people may be interested in home remedies for bacterial vaginosis. While there are some non-prescription treatment options that have been shown to aid in the management or prevention of BV, you should always consult a healthcare provider prior to trying home treatments or remedies for any conditions.

Garlic Tablets

As strange as it may sound, some studies suggest that garlic could be a suitable alternative regime for various infections, including bacterial vaginosis. [11-12] Garlic has antimicrobial properties and has actually been used as a medicinal or therapeutic remedy for hundreds of years. [11] There is still limited data to speak on the efficacy of garlic for BV, but some studies do show that taking garlic tablets may [12-14]:

  • Boost immune system function
  • Prevent some bacterial and fungal infections
  • Provide results similar to metronidazole when taken during a BV episode
  • Improve antibiotic sensitivity

Probiotics

Probiotics are live microorganisms that promote a healthy balance of bacteria in the body. The use of probiotics for treating BV is still being studied, but there are some interesting results. Multiple studies have found that the use of probiotics is thought to be safe and may have beneficial effects for BV treatment. [15-16] One study suggests that probiotics play an important role in maintaining the female reproductive tract, improving vaginal immunity, and treating various gynecological diseases. [17] While results are promising, more research is still needed.

Boric Acid

Boric acid is sometimes recommended by healthcare providers if patients experience recurrent yeast infections or bacterial vaginosis. [18] Boric acid is a compound consisting of hydrogen, boron, and oxygen, that helps promote healthy acid balance in the vagina. [19] In doing so, it can relieve symptoms of some vaginal infections and potentially help prevent and treat BV and yeast infections.

Home remedy treatments are not recommended without consulting a healthcare provider first. Antibiotic treatments are considered the best option for treating BV. If you are experiencing symptoms or believe you may have an infection, speak to a healthcare provider about testing and treatment options. Learn: What Happens If BV Goes Untreated?

Can You Have Sex While Treating BV?

As previously mentioned, bacterial vaginosis is not considered a sexually transmitted infection. This means that you cannot transmit BV to someone else while having sex. While BV isn’t considered an STI, sexual activity can still increase the risk of primary or recurring BV. [1,4] The CDC recommends that anyone being treated for BV refrain from sexual activity or use protection consistently while being treated. [4]

Everlywell Supports Women’s Health

BV is a common vaginal condition that shares similar symptoms with many other vaginal infections, including some STIs, yeast infections, and others. Taking control of your sexual and reproductive health can be as easy as ordering an at-home lab test online or speaking with a licensed healthcare provider through a telehealth consultation. Everlywell is proud to offer online women’s health visits so you can get answers, next steps, and peace of mind.

How to Prevent BV: Methods for Preventing Bacterial Vaginosis

What Happens If BV Goes Untreated?

What is Bacterial Vaginosis? Causes and Symptoms of BV


References

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  2. Miller EA, Beasley DE, Dunn RR and Archie EA (2016) Lactobacilli Dominance and Vaginal pH: Why Is the Human Vaginal Microbiome Unique? Front. Microbiol. 7:1936. doi: 10.3389/fmicb.2016.01936
  3. Bacterial Vaginosis. Cleveland Clinic. February 6 2023. URL. Accessed June 16 2023.
  4. Bacterial Vaginosis- STI Treatment Guidelines. CDC. Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention. July 22 2021. URL. Accessed June 13 2023.
  5. Antibiotics. Medline Plus. NIH. URL. Accessed June 13 2023.
  6. Nankervis H, Thomas KS, Delamere FM, et al. Scoping systematic review of treatments for eczema. Southampton (UK): NIHR Journals Library; 2016 May. (Programme Grants for Applied Research, No. 4.7.) Chapter 6, Antimicrobials including antibiotics, antiseptics and antifungal agents. Available from: https://www.ncbi.nlm.nih.gov/books/NBK363143/
  7. Weir CB, Le JK. Metronidazole. [Updated 2023 Feb 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539728/
  8. Murphy PB, Bistas KG, Le JK. Clindamycin. [Updated 2023 May 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK519574/
  9. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Tinidazole. [Updated 2020 Feb 20]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK548538/
  10. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Secnidazole. [Updated 2020 Feb 25]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK548222/
  11. Ansary J, Forbes-Hernández TY, Gil E, et al. Potential Health Benefit of Garlic Based on Human Intervention Studies: A Brief Overview. Antioxidants (Basel). 2020;9(7):619. Published 2020 Jul 15. doi:10.3390/antiox9070619
  12. Tesfaye A. Revealing the Therapeutic Uses of Garlic (Allium sativum) and Its Potential for Drug Discovery. ScientificWorldJournal. 2021;2021:8817288. Published 2021 Dec 30. doi:10.1155/2021/8817288
  13. Li G, Ma X, Deng L, et al. Fresh Garlic Extract Enhances the Antimicrobial Activities of Antibiotics on Resistant Strains in Vitro. Jundishapur J Microbiol. 2015;8(5):e14814. Published 2015 May 31. doi:10.5812/jjm.14814
  14. Mohammadzadeh F, Dolatian M, Jorjani M, Alavi Majd H, Borumandnia N. Comparing the therapeutic effects of garlic tablet and oral metronidazole on bacterial vaginosis: a randomized controlled clinical trial. Iran Red Crescent Med J. 2014;16(7):e19118. doi:10.5812/ircmj.19118
  15. Wang Z, He Y, Zheng Y. Probiotics for the Treatment of Bacterial Vaginosis: A Meta-Analysis. Int J Environ Res Public Health. 2019;16(20):3859. Published 2019 Oct 12. doi:10.3390/ijerph16203859
  16. Chen R, Li R, Qing W, et al. Probiotics are a good choice for the treatment of bacterial vaginosis: a meta-analysis of randomized controlled trial. Reprod Health. 2022;19(1):137. Published 2022 Jun 13. doi:10.1186/s12978-022-01449-z
  17. Mei Z, Li D. The role of probiotics in vaginal health. Front Cell Infect Microbiol. 2022;12:963868. Published 2022 Jul 28. doi:10.3389/fcimb.2022.963868
  18. Powell A, Ghanem KG, Rogers L, et al. Clinicians' Use of Intravaginal Boric Acid Maintenance Therapy for Recurrent Vulvovaginal Candidiasis and Bacterial Vaginosis. Sex Transm Dis. 2019;46(12):810-812. doi:10.1097/OLQ.0000000000001063
  19. Boric Acid vaginal suppository. Cleveland Clinic. URL. Accessed June 15 2023.
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